Understanding Monkey pox: Outbreaks, Vaccines and Management

Monkeypox is a viral zoonotic disease caused by the monkeypox virus, which is part of the Orthopoxvirus genus, the same genus as the variola virus (which causes smallpox). It was first discovered in laboratory monkeys in 1958 and later identified in humans in 1970 in the Democratic Republic of the Congo.

There is no difference between mpox and monkeypox; they refer to the same disease. “Monkeypox” is the traditional term used for the viral illness caused by the monkeypox virus.

In November 2022, the World Health Organization (WHO) recommended the use of “mpox” as a more neutral term to avoid stigma associated with the word “monkey” and to improve public perception. Both terms refer to the same disease, and the use of “mpox” is intended to help reduce discrimination and promote better understanding of the illness.

Outbreak of Monkeypox

Monkeypox is caused by the monkeypox virus, which is transmitted to humans through contact with infected animals, such as rodents or primates, or through consumption of bushmeat. Human-to-human transmission can occur through close contact with the bodily fluids, respiratory droplets, or lesions of an infected person. Additionally, contaminated materials like bedding or clothing can also serve as transmission routes.

Monkey pox signs

Signs and Symptoms of Monkeypox

The symptoms of monkeypox are similar to but milder than those of smallpox. They typically include:

– Initial Phase: Fever, headache, muscle aches, backache, swollen lymph nodes, chills, and exhaustion.
– Rash Phase: A rash usually develops within 1 to 3 days after the onset of fever. The rash typically starts on the face and then spreads to other parts of the body. It progresses through several stages: macules, papules, vesicles, pustules, and finally scabs.
The illness can last from 2 to 4 weeks, and while the disease is usually self-limiting, severe cases can occur, especially in individuals with weakened immune systems or those with other health conditions.

Monkeypox Vaccine

The vaccine used to protect against monkeypox is primarily the smallpox vaccine, as there is cross-protection due to the close relationship between the two viruses. The smallpox vaccine, known as ACAM2000, has been used for monkeypox in high-risk populations and outbreak settings. A newer vaccine, JYNNEOS (also known as Imvamune or Imvanex), specifically designed for monkeypox and smallpox, is also available and has been used in recent outbreaks.

Monkey pox vaccine

Monkeypox Treatments

There is no specific antiviral treatment for monkeypox, but supportive care can help manage symptoms and improve outcomes. Treatments may include:

– Antiviral Medications: In some cases, antiviral drugs like tecovirimat (TPOXX), which is approved for smallpox, may be used.
– Symptom Management: Pain relievers, fever reducers, and hydration are essential in managing symptoms.
– Preventing Complications: Ensuring proper wound care and monitoring for secondary infections can help prevent complications.

Isolation and supportive care in a medical setting may be required for severe cases or for those with compromised immune systems.

Overall important aspect, early identification and supportive care which are critical for managing monkeypox effectively, and vaccination remains a key tool in preventing the spread of the disease.

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